Measurement of cyclooxygenase inhibition using liquid chromatography–tandem mass spectrometry
نویسندگان
چکیده
منابع مشابه
Plasma Free Metanephrines Quantitation with Automated Online Sample Preparation and Liquid ChromatographyTandem Mass Spectrometry
Recently, we reported an LC-MS/MS method for measuring Pmets using ion-pairing solid phase extraction (IP-SPE) and porous graphitic carbon (PGC) column chromatography1, 2. Although the method is fast and analytically sensitive, it can be further improved by automating the offline sample preparation with online sample preparation technology, which is more timeand cost-effective. Thermo Scientifi...
متن کاملLiquid Chromatography - Mass Spectrometry
In this article, selected examples of applications of liquid chromatography coupled to mass spectrometry are given. The examples include the analysis of i) impurities in manufactured, pharmaceutical or synthesis products, ii) polyphenols in natural products, and iii) phytohormones in plant extracts. Finally, examples of applications of molecular characterization via flow injection analysis by e...
متن کاملMeasurement of iminodipeptides in the serum of patients with prolidase deficiency using liquid chromatography-mass spectrometry.
Iminodipeptides containing C-terminal proline or hydroxyproline were determined in sera from patients with prolidase deficiency, in their mother's serum, and in the sera of unrelated controls, using liquid chromatography-mass spectrometry with an atmospheric pressure ionization interface system. The separation was carried out on a reversed phase column using 1 g/l aqueous trifluoroacetic acid-m...
متن کاملValidation of the analysis method of 25 pesticide residues in rice using LC-MS/MS device (liquid chromatography-mass spectrometry)
Introduction: In recent years, due to the increase in the use of pesticides in agricultural products and its entry into the human food chain, there has been an increase in concerns about the health of food among people. Therefore, the purpose of conducting this research is to validate the analysis method. 25 pesticide residues in rice using LC-MS/MS. Methods: In this research, a simultaneous an...
متن کاملSimultaneous Analysis of Metabolite Residues from Degradation of Dithiocarbamates in Cereals Using Liquid Chromatography Coupled with Tandem Mass Spectrometry
Background and Objectives: Dithiocarbamates are groups of fungicides used to control pests of agricultural products. Analysis of these pesticides with liquid and gas chromatography instruments is associated with various problems due to the presence of metal groups in the structure of these compounds. Therefore, one of the ways for analysis the pesticides is to check the level of decomposition...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Pharmaceutical and Biomedical Analysis
سال: 2011
ISSN: 0731-7085
DOI: 10.1016/j.jpba.2010.08.001